By Russell Viner
The well-known ABC sequence, as serialised within the BMJ
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The photograph is reproduced with permission from Sutton-Hibbert/Rex. uk). The series will be published as a book in summer 2005. BMJ 2005;330:777–80 Competing interests: None declared. com on 13 January 2009 Papers What is already known on this topic 5 In most trial publications, allocation concealment is unclear or inadequate 6 Unclear or inadequate concealment in publications is associated with an exaggeration of the treatment effect by 20-30%, on average 7 8 9 What this study adds Most often allocation concealment is unclear in trial protocols 10 11 Gatekeepers who sanction protocols should require that adequate methods of allocation concealment be described and used Protocols should be publicly accessible to enhance critical appraisal of trials 12 13 14 15 with the findings of Hill et al and Devereaux et al might reflect the difference in response rate, criteria for adequate concealment, recentness of the included trials, or the strategies for contacting and phrasing the questions to the investigators.
Chan AW, Krleza-Jeric K, Schmid I, Altman DG. Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research. CMAJ 2004;171:735-40. Jüni P, Rutjes AW, Dieppe PA. Are selective COX 2 inhibitors superior to traditional non steroidal anti-inflammatory drugs? BMJ 2002;324:1287-8. Chalmers I, Altman DG. How can medical journals help prevent poor medical research? Some opportunities presented by electronic publishing. Lancet 1999;353:490-3. 8F Corrections and clarifications Use of chaperones in general practice The second letter about chaperones in general practice (“Chaperones protect both parties” by Charlotte Cohen and colleagues) contains an error about the timing of the authors’ survey (BMJ 2005;330:846-7, 9 Apr).
The mental health of children and adolescents in Great Britain. 2nd ed. London: Office for National Statistics, 2000. x Bower P, Garralda E, Kramer T, Harrington R, Sibbald B. The treatment of child and adolescent mental health problems in primary care: a systematic review. Fam Pract 2001;18:373-82. x Hack S, Jellinek M. Early identification of emotional and behavioral problems in a primary care setting. In: Juszczak LFM, ed. Adolescent medicine: state of the art reviews. Philadelphia: Belfus Ha, 1996:335-50.